Translation is the essential process by which all cells manufacture proteins. It is both a critical regulatory node in cellular metabolism and a powerful target for therapeutic intervention. As a postdoctoral research fellow in the Dunham Lab at Emory University, I use structural biology, computational, and biochemical approaches to investigate the macromolecular interactions and small molecules that modulate bacterial translation. My work spans the characterization of novel antibiotics, antibiotic resistance mechanisms, the maintenance of translational fidelity, and RNA degradation machinery implicated in translation regulation.
